It implicates 1 the formation of a hybrid gene at the breakpoint, and also, 2 gain in Xp11pter sequences, and loss of heterozygocity in 11q25qter, with possible implications Hybrid/Mutated GeneBreakpoint for translocation to form NONOTF, PSFTF and ASPSCR1TF oncogenes 2 Keywords Disease i Protooncogene Organismspecific databases DisGeNET i 7030 MalaCards i TF OpenTargets i ENSG Orphanet i , Alveolar soft tissue sarcomaA total of five TF gene fusions (PRCCTF, ASPSCR1TF, SFPQTF, NONOTF, and CLTCTF) and one TFEB gene fusion (MALAT1TFEB) have been identified in RCC tumours and characterized at the mRNA transcript level A multitude of molecular pathways welldescribed in carcinogenesis are regulated in part by TF or TFEB proteins, including
Rt Pcr Findings Identification Of The Aspscr1 Aspl Tfe3 Fusion Download Scientific Diagram
